Randall L Woltjer Selected Research

alpha-Synuclein

1/2020	Trans-synaptic and retrograde axonal spread of Lewy pathology following pre-formed fibril injection in an in vivo A53T alpha-synuclein mouse model of synucleinopathy.
3/2015	Progressive aggregation of alpha-synuclein and selective degeneration of lewy inclusion-bearing neurons in a mouse model of parkinsonism.
9/2007	Quantitative proteomics identifies surfactant-resistant alpha-synuclein in cerebral cortex of Parkinsonism-dementia complex of Guam but not Alzheimer's disease or progressive supranuclear palsy.

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Randall L Woltjer Research Topics

Disease

28	Alzheimer Disease (Alzheimer's Disease) 01/2022 - 07/2002
10	Dementia (Dementias) 01/2020 - 07/2002
8	Cognitive Dysfunction 02/2022 - 07/2010
6	Neuroblastoma 09/2011 - 12/2003
5	Parkinson Disease (Parkinson's Disease) 01/2022 - 07/2002
5	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2020 - 07/2002
4	Neoplasms (Cancer) 01/2016 - 04/2007
3	Tauopathies 01/2021 - 12/2014
3	Parkinsonian Disorders (Parkinsonism) 12/2019 - 09/2007
3	Pantothenate Kinase-Associated Neurodegeneration (Hallervorden-Spatz Disease) 12/2019 - 04/2011
3	Neuroinflammatory Diseases 01/2018 - 01/2007
3	Glioma (Gliomas) 01/2015 - 12/2013
3	Frontotemporal Lobar Degeneration (Degeneration, Frontotemporal Lobar) 03/2014 - 03/2010
3	Frontotemporal Dementia (Semantic Dementia) 03/2014 - 03/2010
2	Multiple Sclerosis 01/2022 - 02/2016
2	Lewy Body Disease (Lewy Body Dementia) 01/2022 - 01/2018
2	Multiple System Atrophy 03/2015 - 07/2002
2	Necrosis 01/2015 - 12/2013
2	Movement Disorders (Movement Disorder) 04/2011 - 07/2002
1	Gaucher Disease (Gaucher's Disease) 01/2022
1	Mental Disorders (Mental Disorder) 01/2021
1	Synucleinopathies 01/2020
1	Dystonia (Limb Dystonia) 12/2019
1	Nervous System Diseases (Neurological Disorders) 01/2019
1	Proteostasis Deficiencies 01/2018
1	Late Onset Disorders 01/2018
1	Neoplasm Metastasis (Metastasis) 01/2016
1	Central Nervous System Diseases (CNS Diseases) 01/2016
1	Meningioma (Meningiomas) 01/2016
1	Infarction (Infarctions) 12/2015
1	Neurodegeneration with brain iron accumulation (NBIA) 12/2015
1	Atrophy 12/2014
1	Viral Encephalitis 05/2014
1	Encephalitis (Encephalitis, Rasmussen) 05/2014
1	Chorea (Rheumatic Chorea) 05/2014
1	Seizures (Absence Seizure) 05/2014
1	Ocular Motility Disorders (Convergence Insufficiency) 05/2014
1	Ataxia (Dyssynergia) 05/2014
1	Autoimmune Diseases of the Nervous System 05/2014
1	Sepsis (Septicemia) 05/2014
1	Hypoxia (Hypoxemia) 01/2014
1	Cerebral Palsy (Spastic Diplegia) 12/2013
1	BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia) 09/2012

Drug/Important Bio-Agent (IBA)

15	Proteins (Proteins, Gene)FDA Link 01/2019 - 12/2003
10	Amyloid (Amyloid Fibrils)IBA 01/2021 - 12/2003
9	Amyloid beta-PeptidesIBA 01/2021 - 12/2003
7	Detergents (Detergent)IBA 07/2010 - 05/2005
4	LipidsIBA 01/2022 - 10/2015
4	Biomarkers (Surrogate Marker)IBA 01/2018 - 01/2014
4	DiglyceridesIBA 01/2018 - 01/2015
4	Peptides (Polypeptides)IBA 09/2011 - 05/2005
3	Apolipoproteins E (ApoE)IBA 01/2021 - 12/2004
3	alpha-SynucleinIBA 01/2020 - 09/2007
3	IronIBA 12/2019 - 04/2011
3	cediranib (AZD2171)IBA 01/2015 - 12/2013
3	ProgranulinsIBA 03/2014 - 03/2010
3	DNA-Binding Proteins (DNA Binding Protein)IBA 03/2014 - 03/2010
2	Carrier Proteins (Binding Protein)IBA 01/2019 - 05/2005
2	GadoliniumIBA 02/2016 - 01/2016
2	Ferrosoferric Oxide (Magnetite)FDA Link 01/2016 - 01/2016
2	Aminobutyrates (Aminobutyric Acid)IBA 12/2015 - 05/2014
2	ApolipoproteinsIBA 12/2015 - 12/2004
2	Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA 01/2015 - 01/2014
2	Quinacrine (Mepacrine)IBA 01/2014 - 12/2013
2	Isradipine (Dynacirc)FDA LinkGeneric 09/2011 - 01/2011
2	CalciumIBA 09/2011 - 01/2011
2	Amyloid beta-Protein Precursor (Amyloid Protein Precursor)IBA 01/2011 - 06/2008
1	Biological ProductsIBA 02/2022
1	Prion ProteinsIBA 01/2020
1	Coenzyme A (CoA)IBA 12/2019
1	Dystroglycans (Dystroglycan)IBA 01/2018
1	syntrophin alpha1IBA 01/2018
1	Phospholipases (Phospholipase)IBA 01/2018
1	dystrobrevinIBA 01/2018
1	gamma-Aminobutyric Acid (GABA)IBA 12/2015
1	UbiquitinIBA 12/2015
1	Fatty Acids (Saturated Fatty Acids)IBA 10/2015
1	phosphatidylethanolamineIBA 10/2015
1	phosphatidal ethanolaminesIBA 10/2015
1	Phosphatidylethanolamines (Cephalins)IBA 10/2015
1	PlasmalogensIBA 10/2015
1	MonoglyceridesIBA 10/2015
1	Alanine (L-Alanine)FDA Link 02/2015
1	Threonine (L-Threonine)FDA Link 02/2015
1	Proteasome Endopeptidase Complex (Proteasome)IBA 01/2015
1	Proteasome InhibitorsIBA 01/2015
1	SC 68896IBA 01/2015
1	Immunoglobulins (Immunoglobulin)IBA 05/2014
1	Pentobarbital (Nembutal)FDA Link 05/2014
1	Adrenal Cortex Hormones (Corticosteroids)IBA 05/2014
1	AutoantigensIBA 05/2014
1	AutoantibodiesIBA 05/2014
1	bafilomycin A1IBA 01/2014
1	Angiogenesis InhibitorsIBA 12/2013
1	Actin Capping ProteinsIBA 12/2013
1	adducinIBA 12/2013
1	Amino Acid Transport System X-AG (Glutamate Transporter)IBA 03/2013
1	plerixafor FDA Link 09/2012

Therapy/Procedure

7	Therapeutics 01/2020 - 01/2007
1	Intravenous Injections 01/2016